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INCI name: Dipeptidep-2, Palmytoyl Tetrapeptide-7, Butylene Glycol, Polysorbate 20, Water
Insufficient lymphatic drainage strongly causes the formation of eye bags and dark circle under the eyes. The contraction of lymphangions, necessary to ensure drainage, depends upon bradykinin. One simple method to increase the lifetime of bradykinin is to inhibit its degradation by ACE.
DermaPep™ A3000 is a mixture of dipeptide-2 and palmitoyl tetrapeptide-7. As an ACE inhibitory peptide, the former has the ability to inhibit the formation of angiotensin II and the degradation of the vasodilator, bradykinin. As the mimic peptide of DHEA, the latter has the ability to regulate baseline levels of IL-6, as well as to suppress UV-stimulated overproduction of IL-6. Both peptides work synergistically to fight effectively against signs of aging around the eyes as well as to protect from the formation of eye bags and dark circle under the eyes.
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